PLEASE ANSWER THESE Questions IN ESSAY FORMAT introduction 200 words body conclusions total of words 1500 without references USE THE REFERENCES BELLOW TO ANSWER THESE Questions. ALSO, ADD SOME REFERENCES TO SUPPORT YOUR ANSWER

Q1 Discuss what is known about the effects of pylori virulence factors such as CagA VacA on host epithelial cells and the implications for the pathogenesis of the disease.

Q2 Discuss the problem of anti-microbial resistance in Helicobacter pylori- include a detailed discussion of the known mechanisms of resistance.

Recommended reading/ viewing Peritonitis and Abdominal Sepsis . Author: Brian James Daley, MD, MBA, FACS, FCCP, CNSC; Chief Editor: Julian Katz,

This article is a simple overview but does contain some images of an abscess in a patient with Crohn’s disease References Backert S, Neddermann M, Maubach G, Naumann M. Pathogenesis of Helicobacter pylori infection. Helicobacter. 2016 Aug 16;21(S1):19–25. Gong Y, Yuan Y. Resistance mechanisms of Helicobacter pylori and its dual target precise therapy. Critical Reviews in Microbiology. Taylor & Francis; 2018 May;44(3):371–92. Janda JM, Abbott SL. The genus Aeromonas: taxonomy, pathogenicity, and infection. Clinical Microbiology Reviews. American Society for Microbiology; 2010 Jan;23(1):35–73. Watanabe K, Watanabe N, Jin M, Matsuhashi T, Koizumi S, Onochi K, et al. Mesenteric lymph node abscess due to Yersinia enterocolitica: case report and review of the literature. Clin J Gastroenterol. 2014 Feb;7(1):41–7.

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